This course considers three periods of major scientific development-the Renaissance, the nineteenth century, and the modern period- to explore the influence new ideas, discoveries, and theories had on the imagination of English writers. We will look at the early modern interplay between magic and science, Romantic and Victorian debates about evolution, and the twentieth-century advent of modern physics as we confront consistent tropes like the mad scientist, the scientist-hero, and the problem of uncertainty. Authors covered may include Shakespeare, Marlowe, Bacon, Shelley, Darwin, Conan Doyle, Stevenson, Auden, McEwan, and Stoppard.